name: Rx Propranolol 
also known as: Rx Inderal; Rx Angilol; Rx Berkolol; Rx Half Inderal; Rx Syprol; Rx Beta-Prograne; Rx Bedranol; Propanolol 
also see: High Blood Pressure; Angina; Supraventricular Tachycardia; Essential Tremor; Beta Blockers 
description: Adult Dosing

High Blood Pressure 80-240 mg PO bid starting w/ 40 mg PO bid, increasing dose every week as needed to max 640 mg/d

Angina 80-120 mg PO bid increasing dose every week.

Migraine Headache prevention 40-60 mg PO qid starting w/ 80 mg PO daily in divided doses tid or qid

Supraventricular Tachycardia 10-30 mg PO tid or qid starting w/ 1-3 mg IV at 1 mg/min, may give 2nd dose 2 min later, followed by doses every q4h

Heart Attack 180-240 mg in divided doses tid or qid

Essential Tremor 40 mg po bid

Glossary Rx Terms

Peds Dosing

High Blood Pressure 1-5 mg/kg/d PO in divided doses q6-12h starting w/ 0.5-1 mg/kg/d PO in divided doses q6-12 to max 8 mg/kg/d

Migraine Headache prevention 0.6-1.5 mg/kg/d PO in divided doses q8h to max 4 mg/kg/d

Supraventricular Tachycardia
2-4 mg/kg/d PO in divided doses q6-8h starting w/ 0.5-1 mg/kg/d PO in divided doses q6-12; Max: 16 mg/kg/d
or
0.01-0.1 mg/kg/dose IV slow push increasing q3-5d

thyrotoxicosis
newborns: 2 mg/kg/d PO in divided doses q6-12h
adolescent 0-40 mg PO q6h

Str. 60 mg, 80 mg, 120 mg, 160 mg, 80 mg/ml, 20 mg/5 ml, 1 mg/ml, 40 mg/5 ml, 10 mg, 20 mg, 40 mg, 60 mg, 80 mg

Glossary Rx Terms 
signs & symptoms: Contraindications/Cautions
asthma
sinus bradycardia, severe
2nd, 3rd degree AV block
cardiogenic shock
CHF
caution in elderly, impaired liver function, impaired renal function, diabetes mellitus

Serious Reactions
congestive heart failure
bronchospasm
agranulocytosis
arrhythmias

Common Reactions
bradycardia
congestive heart failure
nausea
vomiting
abdominal pain
diarrhea
constipation
bronchospasm
alopecia
impotence
pharyngitis
dizziness
insomnia
weakness
fatigue
hallucinations
hypotension
rash

Pregnancy Class: C
Lactation: Safe
Metabolism: liver
Excretion: urine
DEA: not controlled
Mechanism of Action: non-selective beta blocker
 

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Last updated 11/16/2008


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